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Tumors in Patients with Angiosarcoma of the Liver

NICHOLAS J. VIANNA, M.D., M.S.P.H.
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▸Requests for reprints should be addressed to Nicholas J. Vianna, M.D.; Bureau of Environmental Epidemiology and Occupational Health, Tower Building, The Governor Nelson A. Rockfeller Empire State Plaza; Albany, NY 12237.


The New York State Department of Health, Bureau of Environmental Epidemiology and Occupational Health; Albany, New York.


Ann Intern Med. 1981;95(2):185-186. doi:10.7326/0003-4819-95-2-185
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Angiosarcoma of the liver is an exceedingly rare vascular tumor that has been associated with exposure to thorium dioxide, arsenic, and vinyl chloride monomer (1, 2). Using methods previously described (1), the Bureau of Occupational Health, New York State Health Department, developed a registry of all histologically confirmed cases of angiosarcoma of the liver diagnosed in residents of New York State from 1970 through 1975. Detailed medical, social, occupational, familial, and therapeutic histories on each patient were obtained from their closest living relatives and physicians. Slides of all patients included in the registry were reassessed blindly for diagnostic accuracy by

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