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Campylobacter Enteritis in Immune-Deficient Patients

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Grant support: in part by the Medical Research Service of the Veterans Administration; grant RR-0051 from the Division of Research Resources, General Clinical Research Center, and research fellowship AM0738 to Dr. Ahnen from the National Institutes of Health.

▸Requests for reprints should be addressed to William R. Brown, M.D.; Gastroenterology Section (111E), 1055 Clermont Street; Denver, CO 80220.

University of Colorado School of Medicine and the Veterans Administration Medical Center; Denver, Colorado.

Ann Intern Med. 1982;96(2):187-188. doi:10.7326/0003-4819-96-2-187
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This excerpt has been provided in the absence of an abstract.

Chronic or recurrent diarrhea is common in immune-deficient persons, especially those with adult-onset or variable immunodeficiency syndrome (1-3). Chronic inflammatory lesions of the rectum, colon, or small intestine, sometimes treated with sulfasalazine or corticosteroids, have been reported in this population (1, 4-7). Campylobacter jejuni now is recognized as a common cause of diarrhea (8) and sometimes of colitis or ileitis resembling the chronic inflammatory bowel diseases (9, 10). We report the cases of two immune-deficient patients, one with chronic proctitis, who had campylobacter infections.

Patient 1: A 63-year old man had gastric achlorhydria, mild steatorrhea, and hypogammaglobulinemia (serum IgG, 119


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