Chronic or recurrent diarrhea is common in immune-deficient persons, especially those with adult-onset or variable immunodeficiency syndrome (1-3). Chronic inflammatory lesions of the rectum, colon, or small intestine, sometimes treated with sulfasalazine or corticosteroids, have been reported in this population (1, 4-7). Campylobacter jejuni now is recognized as a common cause of diarrhea (8) and sometimes of colitis or ileitis resembling the chronic inflammatory bowel diseases (9, 10). We report the cases of two immune-deficient patients, one with chronic proctitis, who had campylobacter infections.
Patient 1: A 63-year old man had gastric achlorhydria, mild steatorrhea, and hypogammaglobulinemia (serum IgG, 119