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Aortic Pericardial Heterograft Obstruction from Endocarditis

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Supported in part by NHLBI Institutional Training Grant HL 07387, Research Grants HL 18794 and HL 23566.

▸Requests for reprints should be addressed to Wilfred Lam, M.D.; Cardiology Section, University of Illinois Hospital, P.O. Box 6998; Chicago, IL 60680.

Abraham Lincoln School of Medicine, University of Illinois College of Medicine; Chicago, Illinois

Ann Intern Med. 1982;96(3):335-336. doi:10.7326/0003-4819-96-3-335
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The usual hemodynamic consequence of bacterial endocarditis is valvular regurgitation. The development of valvular stenosis from endocarditis on native valves has been rarely reported (1, 2). Findings of a pathologic study by Ferrans and associates (3) of porcine heterograft endocarditis have suggested that prosthetic valve stenosis caused by infected vegetations may be relatively common. Clinical hemodynamic obstruction without valvular regurgitation has not been documented with tissue valve endocarditis and has never been reported with pericardial heterograft endocarditis. We report a case of bovine pericardial heterograft endocarditis leading to severe valvular obstruction with no regurgitation.

A 31-year-old male drug addict with


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