0

The full content of Annals is available to subscribers

Subscribe/Learn More  >
Articles |

Predicting Survival in Adults with End-Stage Renal Disease: An Age Equivalence Index

TOM A. HUTCHINSON, M.B.; DUNCAN C. THOMAS, Ph.D.; and BRENDA MACGIBBON, Ph.D.
[+] Article and Author Information

Grant support: by grants from the Conseil de la Recherche en Santé du Québec, the Medical Research Council of Canada, and the Canadian Kidney Foundation.

▸Requests for reprints should be addressed to Tom A. Hutchinson, M.B.; Room A4.17, Department of Medicine, Royal Victoria Hospital; 687 Pine Avenue West; Montreal, Quebec H3A 1A1, Canada.


Montreal, Quebec,Canada


© 1982 American College of PhysiciansAmerican College of Physicians


Ann Intern Med. 1982;96(4):417-423. doi:10.7326/0003-4819-96-4-417
Text Size: A A A

To quantify prognosis in patients with end-stage renal disease, we evaluated pretreatment clinical state and ascertained the outcome of all 220 patients who began therapy at two hospitals from 1970 to 1975. Each of three pretreatment characteristics made a statistically significant independent contribution to the relative risk of death: age (relative risk for 10-year increments = 2.2, p < 0.001); duration of diabetes (relative risk for 10-year increments = 2.2, p < 0.001); and left-sided heart failure (relative risk = 2.0, p < 0.001). We combined the effects of these factors in an age-equivalence index that showed a strong gradient in survival rates from lower to higher values; the 5-year survival rate differed between 92% in patients with a score of 30 or less and 6% in patients with a score over 70. This index, which is simple to use, should prove helpful in patient care and can improve the scientific validity of therapeutic comparisons in patients with end-stage renal disease by identifying and adjusting for the selection biases that occur in the allocation of different treatments.

Figures

Tables

References

Letters

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Comments

Submit a Comment
Submit a Comment

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.

Toolkit

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Advertisement
Related Articles
Related Point of Care
Topic Collections
PubMed Articles
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.
(Required)
(Required)