0

The full content of Annals is available to subscribers

Subscribe/Learn More  >
Brief Communications |

Scintigraphic Thyroid Abnormalities after Radiation: A Controlled Study with 99mTc Pertechnetate Scanning

CLlCERlO GONZALEZ-VILLALPANDO, M.D.; LAWRENCE A. FROHMAN, M.D.; CARLOS BEKERMAN, M.D.; MURRAY J. FAVUS, M.D.; STEPHEN PINSKY, M.D.; U. YUN RYO, M.D., Ph.D.; EILEEN SHOREFREEDMAN, M.S.; and ARTHUR B. SCHNEIDER, M.D., Ph.D.
[+] Article and Author Information

Grant support: research grant CA21518, National Cancer Institute. Dr. Schneider is the recipient of a National Institute of Health Research Career Development Award AM00103.

▸ Requests for reprints should be addressed to Arthur B. Schneider, M.D., Ph.D.; Department of Medicine, Michael Reese Hospital, 2900 South Ellis Avenue; Chicago, IL 60616.


Chicago, Illinois


©1982 American College of PhysiciansAmerican College of Physicians


Ann Intern Med. 1982;97(1):55-58. doi:10.7326/0003-4819-97-1-55
Text Size: A A A

We did 99mTc-pertechnetate thyroid scintigraphy on 99 subjects with no history of therapeutic irradiation to the head or neck. They were compared with 198 irradiated patients selected from a group of over 1700 who were evaluated because of radiation treatment for benign head and neck conditions during childhood. The two groups were similar with respect to age and sex distribution. There were significantly more abnormal scintigrams in the irradiated group (55 of 198 patients versus one of 99 controls). Even after patients and controls with palpable nodules were excluded from the analysis there were still more abnormal scintigrams in the irradiated group (16 of 150 irradiated versus one of 97 control subjects). We conclude that thyroid nodules, including the smaller, nonpalpable nodules discovered by scintigraphy, are related to previous radiation therapy. For persons at substantial risk, such as those who received high-dose treatment (greater than 700 R) during childhood, the data support the use of screening scintigraphy, even with normal findings on palpation.

Topics

thyroid

Figures

Tables

References

Letters

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Comments

Submit a Comment
Submit a Comment

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.

Toolkit

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Advertisement
Related Articles
Related Point of Care
Topic Collections
PubMed Articles
Congenital thyroid hemiagenesis with multinodular goiter. Acta Radiol Short Rep 2014;3(9):2047981614530286.
Could Red Cell Distribution Width be a Marker in Hashimoto's Thyroiditis? Exp Clin Endocrinol Diabetes 2014;122(10):572-574.
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.
(Required)
(Required)