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Cure of Histiocytic Lymphoma

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Grant support: in part by grant CA-14599, U. S. Public Health Service; the Joanne Heppes Fund, the Goldblatt Brothers Employees Nathan Goldblatt Cancer Research Fund, and the Jean Heiman Fund.

Department of Medicine and Cancer Research Center, University of Chicago; Chicago, Illinois

Ann Intern Med. 1982;97(2):274-275. doi:10.7326/0003-4819-97-2-274
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The curability of patients with Hodgkin's disease of all stages improved from a 5-year survival rate in 1940 of 6% to a 5-year actuarial estimated survival rate in 1970 of over 75% (1). During this same 30-year period the survival statistics reported for "reticulum cell sarcoma" (the diagnostic entity coded in national statistical analyses before acceptance of the term "histiocytic lymphoma") remained at a dismal 5-year survival rate of 18% or lower (2).

The knowledge gained from the cure of Hodgkin's disease together with new conceptual approaches and the development of new drugs and drug combinations have permitted novel approaches


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