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Therapy of Experimental Babesiosis

KENNETH S. ROWIN, M.D.; HERBERT B. TANOWITZ, M.D.; and MURRAY WITTNER, M.D., Ph.D.
[+] Article and Author Information

Grant support: grants 1-T32-AI-07183 and AI-12770, National Institutes of Health.

▸Requests for reprints should be addressed to Murray Wittner, M.D., Ph.D. Division of Parasitology, Department of Pathology, Albert Einstein College of Medicine, 1300 Morris Park Avenue; Bronx, NY 10461.


Bronx, New York


© 1982 American College of PhysiciansAmerican College of Physicians


Ann Intern Med. 1982;97(4):556-558. doi:10.7326/0003-4819-97-4-556
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Babesia microti infections established in hamsters were treated successfully with clindamycin. Regimens that contained this drug consistently cleared the infection rapidly and without relapse once the drug was discontinued. Late in the course of the infection, the addition of quinine, through the oral but not parenteral route, to clindamycin therapy, was more effective than clindamycin alone. Both clindamycin and the combination of clindamycin and oral quinine are safe, effective treatments for life-threatening babesiosis.

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babesiosis

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