The first edition of this book, published in 1968, was authoritative for its day and had 21 contributors, 750 pages, and 10-by-6.5-in. page size, and cost $32.75. Now, 14 years later, a second edition has 29 contributors, 895 pages, an 11-by-8-in. format (50% more type per page), and costs $96.00. Although bigger is not always better, in this case it is.
Newer techniques in endocrine pathology, notably electron microscopy and immunocytochemistry (immunoperoxidase staining) have provided new information. New concepts have been proposed, notably in neuroendocrinology, the amine-precursor uptake decarboxylation (APUD) system, and the role of endocrine receptors. New refinements have