0

The full content of Annals is available to subscribers

Subscribe/Learn More  >
Articles |

Opportunistic Infections and Kaposi's Sarcoma Among Haitians: Evidence of a New Acquired Immunodeficiency State

ARTHUR E. PITCHENIK, M.D.; MARGARET A. FISCHL, M.D.; GORDON M. DICKINSON, M.D.; DANIEL M. BECKER, M.D.; ARTHUR M. FOURNIER, M.D.; MARK T. O'CONNELL, M.D.; ROBERT M. COLTON, M.D.; and THOMAS J. SPIRA, M.D.
[+] Article and Author Information

Grant support: in part by funds from the Department of Medicine, University of Miami School of Medicine, Miami, Florida.

▸Requests for reprints should be addressed to Arthur E. Pitchenik, M.D.; University of Miami School of Medicine, Department of Medicine, R-60; P.O. Box 016960; Miami, FL 33101.


Miami, Florida; and Atlanta, Georgia


© 1983 American College of PhysiciansAmerican College of Physicians


Ann Intern Med. 1983;98(3):277-284. doi:10.7326/0003-4819-98-3-277
Text Size: A A A

Twenty Haitian patients, hospitalized from 1 April 1980 to 20 June 1982, had Pneumocystis carinii pneumonia, central nervous system toxoplasmosis, esophageal candidiasis, cryptococcosis, disseminated cytomegalovirus, progressive herpes simplex virus, chronic enteric coccidiosis, or invasive Kaposi's sarcoma. Ten patients died. Opportunistic infections were frequently multiple and were recurrent in three patients. In seven patients disseminated tuberculosis preceded the other infections by 2 to 15 months. There was no evidence of an underlying immunosuppressive disease, and no history of homosexuality or intravenous drug abuse. At least three patients probably acquired the syndrome in Haiti. Lymphadenopathy was common. Seventeen patients tested had anergy, and 18 had lymphopenia. Monoclonal antibody analysis of peripheral-blood T-cell subsets done on 11 patients showed a marked decrease in T-helper cells and an inversion of the normal ratio of T-helper cells to T-suppressor cells. This syndrome among heterosexual Haitians is strikingly similar to the syndrome of immunodeficiency described recently among American homosexuals.

Figures

Tables

References

Letters

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Comments

Submit a Comment
Submit a Comment

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.

Toolkit

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Advertisement
Related Articles
Related Point of Care
Topic Collections
PubMed Articles
The new epidemic. Am J Nurs 2014;114(3):50-1.
Ocular manifestations seen in HIV. Dis Mon 2014;60(6):268-75.
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.
(Required)
(Required)