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Identification of Peritoneal Dialysis Catheter Tunnel Infection by Scanning with Indium-111-Labeled Leukocytes

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▸Requests for reprints should be addressed to Robert W. Steiner, M.D.; Mail Code H 781, 225 Dickinson Street; San Diego, CA 92103.

University Hospital, University of California at San Diego, San Diego ; and the San Diego Veterans Administration Medical Center, La Jolla, California.

Ann Intern Med. 1983;99(1):44-45. doi:10.7326/0003-4819-99-1-44
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During peritoneal dialysis, resistant foci of infection along the intra-abdominal course of the two-cuff peritoneal dialysis catheter (so-called "tunnel infections") frequently lead to relapsing or refractory peritonitis (1, 2). These infections can be difficult to identify before surgical catheter removal. Indium-111-labeled leukocyte scanning was done in an attempt to identify such tunnel infections by a noninvasive method.

Patients had images taken of anterior, posterior, and lateral views, using autologous leukocytes labeled with 500 µCi of indium-111-oxine (MediPhysics Radiopharmaceutical, Emeryville, California) (3). Scans were done 24 hours after blood was drawn, and leukocytes were separated, labeled, and reinjected; during the interval


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