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Heparin-Associated Thrombosis Without Thrombocytopenia

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▸Requests for reprints should be addressed to Brian K. Phelan, M.D.; Division of Cardiology, Vanderbilt University Medical Center, 22nd Avenue South, Nashville, TN 37203.

North Carolina Memorial Hospital, University of North Carolina; Chapel Hill, North Carolina.

Ann Intern Med. 1983;99(5):637-638. doi:10.7326/0003-4819-99-5-637
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This excerpt has been provided in the absence of an abstract.

Heparin-associated thrombocytopenia is a recognized syndrome characterized by persistent thrombocytopenia after heparin administration and the occurrence of arterial thrombosis ( 1 ). The following case report shows that the thromboembolic complications can occur with normal absolute platelet counts as well.

A 64-year-old woman had intra-aortic balloon insertion and right coronary angioplasty for unstable angina with a 90% right coronary artery occlusion. A nontransmural inferior infarction occurred after angioplasty. The patient had a superior mesenteric artery embolus requiring continuous-infusion heparin, 1000 U/h, as a result of the balloon pump. A massive transmural extension of her previous infarct occurred on day 7


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