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After 20 Years, Liver Transplantation Comes of Age

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University of Pittsburgh School of Medicine; Pittsburgh, Pennsylvania

Ann Intern Med. 1983;99(6):854-856. doi:10.7326/0003-4819-99-6-854
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After 20 years as an experimental procedure, orthotopic liver transplantation for patients with advanced hepatic disease has come of age (1, 2). Survival statistics from the four centers with the most experience suggest that the 1-year survival for children having a hepatic transplant should exceed 70%, whereas that for adults should exceed 50% and may, with more care given to the choice of candidates and experience, approach the level of success being achieved in children (3-7). Late deaths among transplant recipients occurring after the first year of survival are unusual and attrition after 1 year of survival actually approaches that


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