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Bayesian and Non-Bayesian Methods of Inference

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Merck Sharp & Dohme Research Laboratories; West Point, Pennsylvania

Ann Intern Med. 1983;99(6):857-859. doi:10.7326/0003-4819-99-6-857
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Statistics is an indispensable tool in clinical research. Disagreements over the use of various approaches such as those reflected in the letters-to-the-editor section of this issue (1,2) should not dissuade us from the basic issue of how to use statistics to improve research efforts. An understanding of what Bayesian and non-Bayesian methods have to offer will help us make intelligent decisions about which to use in particular situations. We should keep in mind a quotation from Box and Tiao (3), advocates of Bayesian methods, "It is, we believe, equally unhelpful for enthusiasts to seem to claim that Bayesian analysis can




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