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Randomised Controlled Clinical Trials.

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By Bulpitt Christopher J.. . 262 pages. Martinus Nijhoff Publishers; , The Hague, Boston, London: , 1983.. $52.00.


Ann Intern Med. 1983;99(6):888-889. doi:10.7326/0003-4819-99-6-888_3
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Over the past decade, there has been considerable interest in improving the quality of clinical evidence in published literature. Thus, both researchers and readers of clinical literature are devoting time to the study of clinical research methods. This book is a useful addition to the growing number of texts and journal articles teaching the principles of clinical epidemiology and biostatistics. The book is limited to discussing randomised controlled trials of therapeutic interventions and provides an extensive outline and summary of the key features to be considered in doing such trials: ethical considerations, objectives, recruitment of subjects, techniques of randomization, sample-size

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