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Heterosexual and Homosexual Patients with the Acquired Immunodeficiency Syndrome: A Comparison of Surveillance, Interview, and Laboratory Data

MARY E. GUINAN, M.D., Ph.D.; PAULINE A. THOMAS, M.D.; PAUL F. PINSKY, M.P.H.; JAMES T. GOODRICH, M.D.; RICHARD M. SELIK, M.D.; HAROLD W. JAFFE, M.D.; HARRY W. HAVERKOS, M.D.; GARY NOBLE, M.D.; and JAMES W. CURRAN, M.D., M.P.H.
[+] Article and Author Information

▸Requests for reprints should be addressed to Mary E. Guinan, M.D., Ph.D.; AIDS Activity, Center for Infectious Diseases, Centers for Disease Control, 1600 Clifton Road, N.E.; Atlanta, GA 30333.


Atlanta, Georgia; and New York, New York


Ann Intern Med. 1984;100(2):213-218. doi:10.7326/0003-4819-100-2-213
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Homosexual and heterosexual patients with the acquired immunodeficiency syndrome were compared by risk group. Race; diagnoses; history of sexually transmitted diseases, sexual behavior, and drug use; and socioeconomic indicators differed considerably among the risk groups, suggesting different risk factors for acquisition of the syndrome. Patients in the homosexual, intravenous drug user, and Haitian risk groups differed in their serologic response to cytomegalovirus and syphilis testing, presumably due to lifestyle-related exposures. Differences in the rate of recovery of cytomegalovirus, serum levels of IgA and IgG, and antibody titers to Epstein-Barr virus were noted among patients with different diagnoses. We conclude that in studies of risk factors for the acquired immunodeficiency syndrome, patients should be analyzed by risk group and diagnoses.

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