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Implantable and External Infusion Pumps for the Treatment of Thromboembolic Disease in Outpatients

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Grant support: The Clinical Efficacy Assessment Project is funded by the John A. Hartford Foundation.

Quotations in advertisements and other commercial publications of text in the American College of Physicians position papers and Clinical Efficacy Assessment Project Recommendations must be with expressed permission from the Department of Health and Public Policy, American College of Physicians, 4200 Pine Street, Philadelphia, PA 19104.

▸Requests for reprints should be sent to Linda Johnson White; Clinical Efficacy Assessment Project, Department of Health and Public Policy, American College of Physicians, 4200 Pine Street; Philadelphia, PA 19104.

Ann Intern Med. 1984;100(2):305-306. doi:10.7326/0003-4819-100-2-305
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An implantable infusion pump consists of a hollow titanium disk separated into two chambers by a collapsible bellow (1-3). At body temperature the vapor pressure exerted on the bellow by the fluorocarbon in one chamber forces the medication in the other chamber through a regulator, from which it is delivered into the body at a constant rate. The pump is placed below the skin in a procedure similar to that used for a permanent cardiac pacemaker. It is refilled with medication by percutaneous injection through a self-sealing septum. The pump is approximately 3- X 8-cm and it weighs approximately 253 g


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