The full content of Annals is available to subscribers

Subscribe/Learn More  >
Original Research |

Air Travel Hypoxemia with Chronic Obstructive Pulmonary Disease

[+] Article, Author, and Disclosure Information

Presented in part in May 1983 at the annual meeting of the American Thoracic Society, Kansas City, Missouri.

▸Requests for reprints should be addressed to Jeffrey S. Schwartz, M.D.; Denver Pulmonary Associates, 2005 Franklin Street, Suite 350; Denver, CO 80205.

La Jolla, California

© 1984 American College of PhysiciansAmerican College of Physicians

Ann Intern Med. 1984;100(4):473-477. doi:10.7326/0003-4819-100-4-473
Text Size: A A A

Because persons with chronic obstructive pulmonary disease and mild hypoxemia may develop severe hypoxemia during commercial airline flights, we measured arterial blood gas pressures in 13 such patients during a flight in an unpressurized airplane (cabin pressures typical of commercial air travel). At 1650 m, mean arterial Po2 decreased from 68.2 ± 8.5 (SD) mm Hg to 51 ± 9.1 mm Hg, and mean arterial Pco2, from 40.9 ± 0.9 to 37.1 ± 6.4 mm Hg. At 2250 m, mean arterial Po2 and Pco2 were 44.7 ± 8.7 and 36.5 ± 5.8 mm Hg, respectively. No symptoms attributable to hypoxemia occurred. Arterial Po2 measured in patients while breathing room air several weeks before the flight did not correlate with that measured at 1650 m, but arterial Po2 measured less than 2 hours before the flight in room air or a 17.2% oxygen mixture did. Whether a patient will need supplemental oxygen to maintain arterial Po2 above a given value can be predicted from arterial blood samples taken while the patient is breathing a hypoxic gas mixture or room air within 2 hours of the flight.





Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Submit a Comment/Letter
Submit a Comment/Letter

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.


Buy Now for $42.00

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Related Articles
Related Point of Care
Topic Collections
PubMed Articles
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.