The full content of Annals is available to subscribers

Subscribe/Learn More  >
Brief Reports |

Familial Colonic Cancer Without Antecedent Polyposis

[+] Article, Author, and Disclosure Information

Grant support: in part by PHS Grant CA 30667 from the National Cancer Institute; and the Medical Research Service of the Veterans Administration.

▸Requests for reprints should be addressed to C. Richard Boland, M.D.; Gastrointestinal Research Laboratory (151M2), Veterans Administration Medical Center, 4150 Clement Street; San Francisco, CA 94121.

Ann Intern Med. 1984;100(5):700-701. doi:10.7326/0003-4819-100-5-700
Text Size: A A A
This excerpt has been provided in the absence of an abstract.

Colorectal carcinoma is primarily caused by environmental factors (1), but a small subset of patients is unusually susceptible to colonic cancer on a familial basis and virtually all family members who inherit the critical gene can be expected to develop cancer eventually. The best known of these syndromes are familial polyposis coli and Gardner's syndrome, both easily recognizable because multiple adenomatous polyps precede the appearance of carcinoma in the colon. Less commonly recognized are the familial colonic cancer syndromes without antecedent polyposis. Such cases are important to recognize because of the serious implications for relatives of those affected.

A 38-year-old


First Page Preview

View Large
First page PDF preview





Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Submit a Comment/Letter
Submit a Comment/Letter

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.


Buy Now for $42.00

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Related Articles
Journal Club
Topic Collections
PubMed Articles
New era of colorectal cancer screening. World J Gastrointest Endosc 2016;8(5):252-8.
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.