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Choice of Therapy in Young Adults with Hyperthyroidism of Graves' Disease: A Brief, Case-Directed Poll of Fifty-Four Thyroidologists

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▸Requests for reprints should be addressed to John T. Dunn, M.D.; Box 511, University of Virginia Medical Center; Charlottesville, VA 22908.

Charlottesville, Virginia

© 1984 American College of PhysiciansAmerican College of Physicians

Ann Intern Med. 1984;100(6):891-893. doi:10.7326/0003-4819-100-6-891
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We asked 54 thyroidologists how they would treat each of four patients having moderate hyperthyroidism of Graves' disease and a thyroid gland weighing 70 g (three to four times normal). For a 19-year-old woman, 67% of thyroidologists recommended an initial course of therapy with antithyroid drugs, usually for 1 year; 24% favored radioiodine treatments; and 9%, surgery. Choices for treating a 19-year-old man were similar. For a 29-year-old man, 44% of thyroidologists preferred drug therapy; 50%, radioiodine; and 6%, surgery. For a 29-year-old woman, choices were similar to those for the 29-year-old man, except for a slight preference for drugs over radioiodine. If hyperthyroidism recurred after a first course of antithyroid drugs, the consultants favored radioiodine treatments and surgery about equally, except in the 29-year-old man, in whom radioiodine was preferred. This survey shows considerable variation among experts in treating hyperthyroidism in young adults.





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