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Byssinosis: Causes and Practical Control

Ann Intern Med. 1984;101(2):252-254. doi:10.7326/0003-4819-101-2-252
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After it was predicted that the respirable portion of cotton dust triggered tightness in the chest, cough, and shortness of breath in exposed textile workers, the prediction was confirmed and the dust effect shown quantitatively in textile mills in 1970 (1). Since then the nature and source of the agent (s) responsible have been investigated. Assays to determine response have ranged from leukocyte chemotaxis in vitro to panels of susceptible human subjects in model cardrooms. The final arbiter of the response must be the whole population of textile plant workers, as the experience with steaming cotton has shown (2). Candidates




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