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Spontaneous Rupture of the Stomach in a Healthy Adult Man After Sodium Bicarbonate Ingestion

MICHAEL R. MASTRANGELO, M.D.; and EDWARD W. MOORE, M.D.
[+] Article, Author, and Disclosure Information

Grant support: by Research Grant #AM 32130 from the National Institutes of Health. Dr. Mastrangelo is the recipient of an NIH Research Fellowship Award (#AM 07244) from the National Institute of Arthrititis, Diabetes, Digestive, and Kidney Diseases.

▸Requests for reprints should be addressed to Edward W. Moore, M.D.; Box 711, MCV Station, Medical College of Virginia, 12th & Broad Streets; Richmond, VA 23298.


Medical College of Virginia, Virginia Commonwealth University; Richmond, Virginia


Ann Intern Med. 1984;101(5):649-650. doi:10.7326/0003-4819-101-5-649
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This excerpt has been provided in the absence of an abstract.

Spontaneous rupture of the stomach is a rare event that usually is fatal. We report the case of a patient in whom rupture occurred within 1 minute after ingestion of a label-recommended dose of sodium bicarbonate. The patient had surgery and survived. This is the fifth such case reported in the literature.

A 31-year-old white man was apparently in excellent health before the present illness. He had no history of peptic ulcer disease, abdominal trauma, or surgery. At approximately 2000 h on 25 June 1981, the patient began eating dinner at a Mexican restaurant. He had two margueritas, an order

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