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Chemotherapy for Large-Cell Lymphoma: Optimism and Caution

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New York Hospital-Cornell Medical Center; New York, New York

Ann Intern Med. 1985;103(1):140-142. doi:10.7326/0003-4819-103-1-140
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The treatment of large-cell lymphoma is proving to be an exciting page in the unfolding story of cancer chemotherapy. Excitement and optimism are generated by the realization that many of the principles and theories developed in stepwise fashion for cancer chemotherapy may actually be working in the clinic, at least for this tumor. The results achieved in the study reported by Klimo and Connors in the May issue (1) herald the eventuality of cure for almost all patients with large-cell lymphoma, a disease that was usually fatal 15 years ago (2). Of 61 patients treated with the combination chemotherapy regimen


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