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The Revised French-American-British Classification of Acute Myeloid Leukemia: Is New Better?

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University of Minnesota Health Sciences Center; Minneapolis, Minnesota

Ann Intern Med. 1985;103(4):614-616. doi:10.7326/0003-4819-103-4-614
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Since its introduction in 1976, the classification of the acute myeloid leukemias by the French-American-British (FAB) Cooperative Group (1) has deservedly gained wide acceptance. This acceptance has occurred primarily because the classification provides a common language for persons treating and studying acute leukemia. Before widespread adoption of this classification the terminology applied to different forms of acute myeloid leukemia varied and comparison of treatment results among institutions was difficult. The classification has also been shown to have independent prognostic significance for survival (2). An additional factor contributing to its adoption has been its relative ease of use, because diagnosis depends


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