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Bacteremia and Fungemia in Patients with the Acquired Immunodeficiency Syndrome

ESTELLA WHIMBEY, M. D.; JONATHAN W. M. GOLD, M.D.; BRUCE POLSKY, M.D.; JOSÉ DRYJANSKI, M.D.; CATHERINE HAWKINS, M.D.; ANNE BLEVINS, R.N.; PATRICIA BRANNON, B.A.; TIMOTHY E. KIEHN, Ph.D.; ARTHUR E. BROWN, M.D.; and DONALD ARMSTRONG, M.D.
[+] Article, Author, and Disclosure Information

Presented in part at the International Conference on Acquired Immunodeficiency Syndrome in Atlanta, Georgia, 15 April 1985.

▸Requests for reprints should be addressed to Donald Armstrong, M.D.; Infectious Disease Service, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue; New York, NY 10021.


New York, New York


©1986 American College of PhysiciansAmerican College of Physicians


Ann Intern Med. 1986;104(4):511-514. doi:10.7326/0003-4819-104-4-511
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Forty-nine episodes of bacteremia and fungemia occurred in 38 of 336 patients with the acquired immunodeficiency syndrome seen at our institution since 1980. There were five types of infections. Infections commonly associated with a T-cell immunodeficiency disorder comprised 16 episodes and included those with Salmonella species, Listeria monocytogenes, Cryptococcus neoformans, and Histoplasma capsulatum. Infections commonly associated with a B-cell immunodeficiency disorder included those with Streptococcus pneumoniae and Haemophilus influenzae. Infections occurring with neutropenia were caused by Pseudomonas aeruginosa, Staphylococcus epidermidis, and Streptococcus faecalis. Other infections occurring in the hospital were caused by Candida albicans, Staphylococcus epidermidis, enteric gram-negative rods, Staphylococcus aureus, and mixed S. aureus and group G streptococcus. Other infections occurring out of the hospital included those with S. aureus, Clostridium perfringens, Shigella sonnei, Pseudomonas aeruginosa, and group B streptococcus. Because two thirds of the septicemias were caused by organisms other than T-cell opportunists, these pathogens should be anticipated during diagnostic evaluation and when formulating empiric therapy.

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