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Lymphocytic Hypophysitis with Isolated Corticotropin Deficiency

MICHAEL D. JENSEN, M.D.; BARRY S. HANDWERGER, M.D.; BERND W. SCHEITHAUER, M.D.; PAUL C. CARPENTER, M.D.; RITA MIRAKIAN, M.D.; and PETER M. BANKS, M.D.
[+] Article and Author Information

▸Requests for reprints should be addressed to Michael D. Jensen, M.D.; Division of Endocrinology, Metabolism, and Internal Medicine, Mayo Clinic, 200 First Street SW; Rochester, MN 55905.


Rochester, Minnesota; and London, England


© 1986 American College of PhysiciansAmerican College of Physicians


Ann Intern Med. 1986;105(2):200-203. doi:10.7326/0003-4819-105-2-200
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In a 32-year-old woman, acquired, isolated corticotropin deficiency resulted from postpartum lymphocytic hypophysitis. The literature suggests that lymphocytic hypophysitis may cause acquired deficiencies of anterior, and possibly posterior, pituitary hormones. Immunologic evaluation of our patient failed to uncover anticorticotroph antibodies. Prompt recognition of this potentially fatal condition is important because of the availability of effective treatment.

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