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Thyrotoxicosis Presenting with Secretory Diarrhea

KIM S. CULP, M.D.; and VERONICA K. PIZIAK, M.D., Ph.D.
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▸Requests for reprints should be addressed to Kim S. Culp, M.D.; Division of Gastroenterology, Scott and White Memorial Hospital and Clinic, 2401 South 31st Street; Temple, TX 76508.


Scott and White Memorial Hospital and Clinic; Temple, Texas.


Ann Intern Med. 1986;105(2):216-217. doi:10.7326/0003-4819-105-2-216
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BOTH DIARRHEA and constipation have been reported in patients with thyrotoxicosis (1, 2). Although theories support disturbances in gastrointestinal motility as the basis for these symptoms, the responsible mechanisms have yet to be defined (2, 3). Steatorrhea has been reported in hyperthyroidism, and both hyperphagia and hypermotility are believed to play important roles in this form of steatorrhea (4, 5). To our knowledge, secretory diarrhea has not been reported as a gastrointestinal manifestation of thyrotoxicosis.

A 47-year-old woman had severe, watery diarrhea and weakness. She had been healthy until 2 months before admission when she had the insidious onset of

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PubMed Articles
Secretory diarrhea and thyrotoxicosis. Ann Intern Med 1987;106(2):332.
Acute and chronic diarrhea. How to keep laboratory testing to a minimum. Postgrad Med 1994;96(3):30-2, 35-8, 43 passim.
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