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Chronic Hiccups and Gastroesophageal Reflux Disease: The Acid Perfusion Test as a Provocative Maneuver

MICHAEL GLUCK, M. D.; and CHARLES E. POPE II, M.D.
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▸Requests for reprints should be addressed to Michael Gluck, M. D.; Division of Gastroenterology, Veterans Administration Medical Center, 1660 South Columbian Way; Seattle, WA 98108.


Veterans Administration Medical Center, University of Washington; Seattle, Washington .


Ann Intern Med. 1986;105(2):219-220. doi:10.7326/0003-4819-105-2-219
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HICCUPS (singultus) usually provoke a tolerant smile and the prompt application of home remedies. Any impersonation of an inebriated person is not complete without hiccups. However, in an immediate postoperative situation where such violent diaphragmatic contractions can disrupt suture lines, hiccups are not a laughing matter. Intractable hiccups take on a disturbing character to both sufferer and physician. Previous reviews of the topic (1-3) have listed many causes for intractable hiccups, and in all lists one finds "esophagitis and hiatal hernia." Yet, no studies clearly show that an irritated esophagus can produce chronic hiccups.

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