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Growth-Hormone-Releasing Hormone: A Clinical Update

Ann Intern Med. 1986;105(3):447-449. doi:10.7326/0003-4819-105-3-447
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Growth-hormone-releasing hormone (GHRH) is the most recent and last of the classical hypothalamic releasing hormones to be identified. The discovery and characterization of a new hormone affords the scientific and medical community the opportunity to address several questions of potential physiologic and practical importance, as the work with GHRH amply shows. First, it is necessary to determine the in-vitro and in-vivo action, specificity, interaction with other hormones, and any invivo adverse effects. If the hormone is shown to have diagnostic or therapeutic benefit, it may then be made available for general clinical use. At this time in the United States,




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