The full content of Annals is available to subscribers

Subscribe/Learn More  >
Articles |

Higher Risk of Lung Cancer in Chronic Obstructive Pulmonary Disease: A Prospective, Matched, Controlled Study

[+] Article, Author, and Disclosure Information

Presented in part at the Annual Meeting of the American Thoracic Society, Anaheim, California, 12-15 May 1985.

Requests for reprints should be addressed to R. Drew Miller, M.D.; Division of Thoracic Diseases and Internal Medicine, Mayo Clinic, 200 First Street S.W.; Rochester, MN 55905.

Rochester, Minnesota

©1986 American College of PhysiciansAmerican College of Physicians

Ann Intern Med. 1986;105(4):503-507. doi:10.7326/0003-4819-105-4-503
Text Size: A A A

To assess the risk of lung cancer in patients with chronic obstructive pulmonary disease, we matched, on the basis of age, sex, occupation, and smoking history, 113 persons ("cases") who had a forced expiratory volume in 1 second (FEV1) of 70% or less of predicted normal with 113 control persons who had an FEV1 of 85% or more. All persons were observed from 1973-74 through 1984 for a diagnosis of lung cancer, death from lung cancer, and death from any cause. At entry, subjects had an age range of 45 to 59 years; men numbered 186 and women 40. Histologically proven lung cancer developed in 9 cases and in 2 controls, all men. The rate of development of lung cancer was significantly different in the two groups (p = 0.024): the 10-year cumulative percentage was 8. 8% for cases and 2.0% for controls. Overall 10-year survival was estimated to be 74.0% for cases and 91.1% for controls (p < 0.001).





Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Submit a Comment/Letter
Submit a Comment/Letter

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.


Buy Now for $42.00

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Related Articles
Related Point of Care
Topic Collections
PubMed Articles
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.