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Hepatitis A Revisited

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University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, New Jersey

Ann Intern Med. 1986;105(6):960-961. doi:10.7326/0003-4819-105-6-960
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The perception seems widespread that hepatitis A virus does not cause chronic disease, rarely causes fulminant hepatitis, is not associated with extrahepatic manifestations, and results in only a benign, self-limited disease generally confined to underdeveloped countries and occasional foodborne or waterborne outbreaks in this country. Certainly, hepatitis A virus does not match the propensity of hepatitis B virus to cause any of these potentially calamitous complications. Even the elusive non-A, non-B hepatitis viruses, for which a specific serologic marker is still lacking, engender more respect because of their association with post-transfusion hepatitis and chronic liver injury. Also, interest generated by



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