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Free-Base Cocaine Use Associated with Bronchiolitis Obliterans Organizing Pneumonia

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▸Requests for reprints should be addressed to Steven A. Schonfeld, M.D.; Pulmonary Division, Sinai Hospital of Baltimore, 2401 West Belvedere Avenue; Baltimore, MD 21215.

Sinai Hospital of Baltimore; Baltimore, Maryland.

Ann Intern Med. 1987;107(2):186-187. doi:10.7326/0003-4819-107-2-186
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Cocaine abuse is reaching epidemic proportions and its adverse health consequences are widespread (1). Although physiologic derangements have been shown in users of cocaine in "free-base" form (2, 3), to the best of our knowledge this case report is the first clinical and pathologic description of pulmonary toxicity associated with the use of free-base cocaine manifested as bronchiolitis obliterans organizing pneumonia.

A previously healthy 32-year-old man with a 10-day history of nonproductive cough, fever, and dyspnea unresponsive to tetracycline and antitussives was hospitalized. He denied toxic exposures, homosexuality, or travel. He smoked a half pack of cigarettes per day for



cocaine ; boop

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