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Who Goes First?: The Story of Self-Experimentation in Medicine.

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By Altman Lawrence K.. . 430 pages. Random House; , New York: , 1987.. $22.50.

Ann Intern Med. 1987;107(5):793. doi:10.7326/0003-4819-107-5-793_1
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This excerpt has been provided in the absence of an abstract.

Physicians, laymen, and clinical investigators should find this a fascinating book. In nontechnical language it tells the story of an important phenomenon in the history of medical discovery. Self-experimentation has been more widespread than is generally appreciated.

The author, a physician, medical investigator, and eminent professional journalist, has long been fascinated with self-experimentation. He has traveled far and interviewed many medical investigators, especially those who have used themselves as experimental subjects. Hence, in addition to the well-woven historical threads, there are direct accounts from present-day participants. The book's subject is highly relevant to today's rapidly increasing ethical dilemmas stemming from


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