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Cancer and Chemotherapy by Infusion.

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Edited by Lokich Jacob J.. . 747 pages. Precept Press, Inc., Chicago: , 1987.. $99.00.

Ann Intern Med. 1987;107(5):796. doi:10.7326/0003-4819-107-5-796_1
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The future of infusional chemotherapy is uncertain. Despite theoretical considerations and a number of clinical trials by established investigators, several issues continue to impede its acceptance. Stability of agents, hardware capable of handling prolonged infusion schedules, and questions concerning the efficacy of this delivery technique need to be dealt with before practitioners adopt this method. This book examines the current state of infusional chemotherapy technology and explores possible directions for future study.

Included is a review of the pharmacologic rationale, with several authors noting that optimal dose-time schedules for most chemotherapeutic agents and tumor types, using an infusional approach, have


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