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Thymoma, Myasthenia Gravis, and Relapsing Polychondritis

John A. Conti, MD; Alan R. Colicchio, MD; and Leslie M. Howard, MD
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Current Author Addresses: Dr. Conti: Department of Medicine, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103.

Dr. Colicchio: Department of Neurology, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103.

Dr. Howard: Hematology and Oncology Section, Medical Service Department, Veterans Administration Medical Center, East Orange, NJ 07019.

Ann Intern Med. 1988;109(2):163-164. doi:10.7326/0003-4819-109-2-163
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This excerpt has been provided in the absence of an abstract.

The association of thymoma with myasthenia gravis is well established (1). We describe a patient in whom thymoma and myasthenia gravis occurred together with relapsing polychondritis. This is the first association of relapsing polychondritis with thymoma, myasthenia gravis, or both.

A 64-year-old white man was hospitalized in December 1985 with a 9-month history of generalized weakness, severest in his shoulders and neck muscles, associated with ptosis, and difficulty in chewing and swallowing. All symptoms progressively worsened and partially subsided with rest. Four months earlier, pain and redness of his nose and right ear had occurred for 1 week, and cleared


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