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Acute Orchitis in Familial Mediterranean Fever

Gidgeon Eshel, MD; Deborah Zemer, MD; and Avihu Bar-Yochai, MD
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Requests for Reprints: G. Eshel, MD, Assaf-Harofeh Medical Center, Department of Pediatrics A, Zrifin 70300, Israel.

Current Author Addresses: Drs. Eshel and Bar-Yochai: Department of Pediatrics A, Assaf Harofeh Medical Center, Zrifin 70300 Israel.

Dr. Zemer: Heller Institute of Medical Research, Sheba Medical Center, Sackler Medical School, Tel-Aviv University, Israel.

Ann Intern Med. 1988;109(2):164-165. doi:10.7326/0003-4819-109-2-164
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This excerpt has been provided in the absence of an abstract.

Familial Mediterranean fever is a genetic disease characterized by acute febrile attacks and development of generalized AA-amyloidosis. The attacks usually last 24 to 72 hours and recur at irregular intervals. They involve serous membranes and appear as peritonitis, pleuritis, or synovitis (1). We report 20 episodes of acute, unilateral, short-term orchitis in 13 patients with familial Mediterranean fever (Table 1).

The attacks of orchitis occurred together with an abdominal attack or alone. They were self-limited, lasting 24 to 72 hours, and were followed by complete spontaneous recovery with no apparent sequelae. The attacks were similar to the typical febrile attacks


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