The full content of Annals is available to subscribers

Subscribe/Learn More  >
Reviews |

Syndromes of Vibrio vulnificus Infections: Clinical and Epidemiologic Features in Florida Cases, 1981-1987

Karl C. Klontz, MD, MPH; Spencer Lieb, MPH; Minnie Schreiber, MS; Henry T. Janowski, MPH; Linda M. Baldy, MPH; and Robert A. Gunn, MD, MPH
[+] Article, Author, and Disclosure Information

Requests for Reprints: Karl C. Klontz, MD, Preventive Health Services, Health and Rehabilitative Services, 1317 Winewood Blvd., Tallahassee, FL 32399-0700.

Current Author Addresses: Dr. Klontz: Division of Field Services (Assigned to the Florida Department of Health and Rehabilitative Services), Epidemiology Program Office, Centers for Disease Control, Atlanta, GA 30333.

Mr. Lieb and Mr. Janowski: Preventive Health Services, Florida Department of Health and Rehabilitative Services, Tallahassee, FL 32399-0700. Ms. Schreiber, Central Laboratory, Florida Department of Health and Rehabilitative Services, Jacksonville, FL 32601.

Ms. Baldy: Tallahassee Branch Library, Florida Department of Health and Rehabilitative Services, Tallahassee, FL 32399-0700. Dr. Gunn: Epidemiology Program Office, Centers for Disease Control, Atlanta, GA 30333.

©1988 American College of PhysiciansAmerican College of Physicians

Ann Intern Med. 1988;109(4):318-323. doi:10.7326/0003-4819-109-4-318
Text Size: A A A

Study Objective: To describe the clinical and epidemiologic features of Vibrio vulnificus infections.

Design: Case series based on notifiable disease report forms and patient medical records.

Setting: Cases reported to the Florida Department of Health and Rehabilitative Services from 1981 to 1987.

Patients: Sixty-two patients with V. vulnificus infection.

Measurements and Main Results: The three clinical syndromes found were primary septicemia (38 patients), wound infections (17 patients), and gastrointestinal illness without septicemia or wound infections (7 patients). Mortality rate was highest for patients with primary septicemia (55%; 95% CI, 38 to 71) and intermediate for wound infections (24%; 95% CI, 8 to 51); no deaths occurred in those with gastrointestinal illness. Common characteristics and exposures in patients with these syndromes included recent history of raw oyster consumption for primary septicemia and gastrointestinal illness, liver disease for primary septicemia, and either having a preexisting wound or sustaining a wound in contact with seawater for wound infections.

Conclusions: Clinicians should ask about marine exposures in patients with underlying medical conditions, especially liver disease, who present with unexplained febrile illness, and should start appropriate therapy promptly.





Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Submit a Comment/Letter
Submit a Comment/Letter

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.


Buy Now for $42.00

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Related Articles
Topic Collections
PubMed Articles
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.