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Relapsing Polychondritis and Cardiac Valvular Involvement

William VanDecker, MD; and Ioannis P. Panidis, MD
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Requests for Reprints: Ioannis P. Panidis, MD; Cardiac Ultrasound Laboratory, Temple University Hospital, 9th Floor, Pavillion Building, 3401 N. Broad Street, Philadelphia, PA 19104.

Current Author Addresses: Drs. VanDecker and Panidis: Division of Cardiology, Department of Medicine, Temple University School of Medicine, Philadelphia, PA 19104.

Ann Intern Med. 1988;109(4):340-341. doi:10.7326/0003-4819-109-4-340
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Relapsing polychondritis is an inflammatory disorder of cartilage in the spectrum of rheumatic vasculitides. The disease usually affects middle-aged men and is manifested by auricular and nasal chondritis, fever, seronegative arthritis, laryngeal and tracheal symptoms, audiovestibular complaints, ocular inflammation, and a saddle nose (1-3). There have been occasional reports of cardiovascular involvement (4-8). We report the case of a patient with relapsing polychondritis who developed severe aortic and mitral regurgitation requiring double-valve replacement.

A 54-year-old black man with a history of intravenous drug abuse in the distant past had relapsing polychondritis determined by waxing and waning auricular and nasal septal


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