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Mycobacterium avium Complex Infection Presenting as Endobronchial Lesions in Immunosuppressed Patients

Steven J. Packer, MD; Thomas Cesario, MD; and James H. Williams Jr., MD
[+] Article and Author Information

Requests for Reprints: James H. Williams, Jr., MD, University of California, Irvine Medical Center, Pulmonary/Medicine ... Route 81, 101 City Drive South, Orange, CA 92668.

Current Author Addresses: Dr. Williams: University of California, Irvine Medical Center, Pulmonary/Medicine ... Route 81, 101 City Drive South, Orange, CA 92668.

Dr. Cesario: University of California, Irvine Medical Center, Infectious Diseases/Medicine, Route 81, 101 City Drive South, Orange, CA 92668. Dr. Packer: 23845 Homan Hwy, #220, Monterey, CA 93940.


©1988 American College of PhysiciansAmerican College of Physicians


Ann Intern Med. 1988;109(5):389-393. doi:10.7326/0003-4819-109-5-389
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Infections caused by Mycobacterium avium in relatively immunocompetent hosts usually occur with isolated pulmonary involvement. Patients with the acquired immunodeficiency syndrome (AIDS) more commonly have disseminated disease. Endobronchial masses, however, have not been described with M. avium complex infections in normal or compromised hosts. We describe the cases of two patients with AIDS, both receiving zidovudine therapy, who presented with endobronchial obstruction and hilar adenopathy. Results of radiographic and endobronchial examination of these lesions suggested malignancy. Histologic and microbiologic tests, however, showed M. avium, and the lesions responded remarkably to mechanical debridement and anti-mycobacterial therapy.

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