The full content of Annals is available to subscribers

Subscribe/Learn More  >
Brief Reports |

Maintenance Amphotericin B for Cryptococcal Meningitis in the Acquired Immunodeficiency Syndrome (AIDS)

Abigail Zuger, MD; Michael Schuster, MD; Michael S. Simberkoff, MD; James J. Rahal, MD; and Robert S. Holzman, MD
[+] Article, Author, and Disclosure Information

This paper was presented in part at the Second International Conference on AIDS held 23 to 25 June 1986 in Paris, France.

Requests for Reprints: Robert S. Holzman, MD, Department of Medicine, New York University School of Medicine, 550 First Avenue, New York, NY 10016.

Current Author Addresses: Drs. Zuger and Holzman: Department of Medicine, New York University School of Medicine. New York, NY 10016.

Dr. Simberkoff: New York Veterans Administration Medical Center, New York, NY 10010.

Dr. Schuster: Department of Medicine, Goldwater Memorial Hospital, New York, NY 10044.

Dr. Rahal: Booth Memorial Medical Center, Flushing, NY 11355.

Ann Intern Med. 1988;109(7):592-593. doi:10.7326/0003-4819-109-7-592
Text Size: A A A

We previously reported our experience (1) with the treatment of cryptococcal infections in patients with the acquired immunodeficiency syndrome (AIDS). Like other investigators (2, 3) we noted a high relapse rate and a poor response to treatment among patients with relapsed infections. Continued weekly infusions of amphotericin B after a standard course of therapy seemed to offer our patients some protection against relapse. Of seven patients who received maintenance therapy with amphotericin B, none had relapses; four of eight patients had relapses when maintenance therapy was not administered. This observation prompted us to recommend maintenance amphotericin B for all patients





Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Submit a Comment/Letter
Submit a Comment/Letter

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.


Buy Now for $42.00

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Related Articles
Topic Collections
PubMed Articles
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.