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Corticosteroids in Severe Alcoholic Hepatitis

Martin Black, MD; and Anthony S. Tavill, MD
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Requests for Reprints: Martin Black, MD, Department of Medicine, Temple University School of Medicine, 3420 North Broad Street, Philadelphia, PA 19140.

Ann Intern Med. 1989;110(9):677-680. doi:10.7326/0003-4819-110-9-677
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Alcoholic hepatitis is the term for a clinicopathologic syndrome resulting from prolonged excessive alcohol consumption characterized by an acute or subacute clinical presentation and a distinctive appearance on liver biopsy (which can be seen also in the absence of an acute or subacute clinical presentation). The syndrome appears to be a relatively infrequent manifestation of alcohol hepatotoxicity and may occur early or late in the course of exposure to alcohol. Although most patients have or will develop a full-fledged cirrhosis, a clinically recognizable (or diagnosed) episode of alcoholic hepatitis is identified in a minority of alcoholic patients who subsequently develop


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