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Intravenous Amiodarone during Prolonged Resuscitation from Cardiac Arrest

Marcus L. Williams, MD; Alan Woelfel, MD; Wayne E. Cascio, MD; Ross J. Simpson Jr., MD; Leonard S. Gettes, MD; and James R. Foster, MD
[+] Article and Author Information

Grant Support: Supported in part by NHLBI grants 27430 and HL 07470.

Requests for Reprints: James R. Foster, MD, Division of Cardiology, CB #7075, Burnett-Womack Building, University of North Carolina School of Medicine, Chapel Hill, NC 27599.

Current Author Addresses: Drs. Williams, Woelfel, Cascio, Simpson, Gettes, and Foster: Division of Cardiology, University of North Carolina School of Medicine, Chapel Hill, NC 27599.


Ann Intern Med. 1989;110(10):839-842. doi:10.7326/0003-4819-110-10-839
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Because only 13% of patients with in-hospital cardiac arrest survive to discharge from the hospital (1, 2), with none surviving when resuscitation exceeds 30 minutes (1), there is an urgent need for more effective means of treating hospitalized patients with cardiac arrest. Intravenous amiodarone may produce rapid control of frequently recurring ventricular tachycardia when given outside the setting of cardiac arrest (3-7). Therefore, we administered amiodarone intravenously to 14 patients during prolonged in-hospital resuscitation from refractory cardiac arrest due to ventricular tachycardia or ventricular fibrillation from October 1982 through February 1988. Clinical details, obtained from review of hospital records, are

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