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Acute Asthma Attack Due to Ophthalmic Indomethacin

Gerard J. Sheehan, MB; Morley R Kutzner, MD; and Wu D. Chin, MB
[+] Article and Author Information

Requests for Reprints: Gerard J. Sheehan, MB, Room 2Fl.29, W.C. MacKenzie Health Sciences Centre, University of Alberta Hospital, Edmonton, Alberta, Canada T6G 2B7.

Current Author Addresses: Dr. Sheehan: Room 2Fl.29, W.C. MacKenzie Health Sciences Centre, University of Alberta Hospital, Edmonton, Alberta, Canada T6G 2B7.

Dr. Kutzner: 1802 Royal Trust Tower, Edmonton, Alberta, Canada T5J 2Z2.

Dr. Chin: Room 2E4.43, Department of Medicine, W.C. MacKenzie Health Sciences Centre, University of Alberta Hospital, Edmonton, Alberta, Canada T6G 2B7.


Ann Intern Med. 1989;111(4):337-338. doi:10.7326/0003-4819-111-4-337
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This excerpt has been provided in the absence of an abstract.

Ophthalmic timolol has recently been recognized as a cause of exacerbation of asthma. Recently we encountered another ophthalmic solution, indomethacin, that caused a life-threatening episode in an asthmatic patient.

Case Report: A 79-year-old woman had a long history of adult-on-set asthma treated by inhaled salbutamol and beclomethasone. Two years before, she had a myocardial infarction and subsequently received regular furosemide for cardiac failure. She had chronic hypertension for which she received nifedipine. In 1980, she had bilateral cataract extractions. Because of difficulty tolerating contact lenses, in 1987 a lens was surgically implanted. After surgery, she was treated with topical tapering

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