The full content of Annals is available to subscribers

Subscribe/Learn More  >
Brief Reports |

The Eosinophilia-Myalgia Syndrome with Neuritis Associated with L-Tryptophan Use

Randi M. Dicker, BS; Nicholas James, MD; and Burke A. Cunha, MD
[+] Article, Author, and Disclosure Information

Requests for Reprints: Burke A. Cunha, MD, Infectious Disease Section, Winthrop-University Hospital, Mineola, NY 11501.

Current Author Addresses: Ms. Dicker: State University of New York at Stony Brook, School of Medicine, Health Sciences Center, Stony Brook, NY 11790.

Dr. James: 230 Hilton Avenue, Suite 20, Hempstead, NY 11550.

Dr. Cunha: Infectious Disease Section, Winthrop-University Hospital, Mineola, NY 11501.

Ann Intern Med. 1990;112(12):957-958. doi:10.7326/0003-4819-112-12-957
Text Size: A A A
This excerpt has been provided in the absence of an abstract.

The eosinophilia-myalgia syndrome, the recently described disorder (1, 2) associated with the use of L-tryptophan, may present with neuritis, among other features. A history of L-tryptophan use should be sought in patients presenting with symptoms of this disorder, particularly those with anxiety, depression, or insomnia. We report the case of a patient in which the neuritis was a prominent aspect of the syndrome.

Case Report: A 48-year-old woman sought medical attention because of increasingly severe muscle aches. Six weeks before she was hospitalized, the patient had upper-back aches and soreness. The pain worsened, progressing to her shoulders, upper arms, thighs,


First Page Preview

View Large
First page PDF preview





Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Submit a Comment/Letter
Submit a Comment/Letter

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.


Buy Now for $42.00

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Related Articles
Topic Collections
PubMed Articles
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.