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Pancreatic Carcinoma as a Cause of Unexplained Pancreatitis: Report of Ten Cases

Albert Lin, MD; and Edward R. Feller, MD
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Requests for Reprints: Edward R. Feller, MD, One Randall Square, Providence, RI 02904.

Current Author Addresses: Dr. Lin: Medicine Branch, National Cancer Institute, National Institutes of Health, Building 10, Room 12N-228, Bethesda, MD 20892.

Dr. Feller: One Randall Square, Providence, RI 02904.

Ann Intern Med. 1990;113(2):166-167. doi:10.7326/0003-4819-113-2-166
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We studied ten patients with documented pancreatic carcinoma who initially presented with acute onset of abdominal pain and hyperamylasemia typical of acute pancreatitis. We report this unusual association of these common diseases to alert clinicians to consider underlying carcinoma in unexplained acute pancreatitis.

Patients and Methods: Records from March 1978 to December 1987 of patients with pancreatic carcinoma were reviewed retrospectively in two hospitals affiliated with Brown University. Ten patients (3.0% of 302 patients with pancreatic carcinoma; 95% confidence interval [CI], 2.01% to 3.99%) were identified in whom acute pancreatitis was the initial clinical feature of a subsequently proven pancreatic


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