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Allergic Bronchopulmonary Aspergillosis with Adenopathy

Christina E. Hantsch, BS; and Tonny Tanus, MD
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Requests for Reprints: Tonny Tanus, MD, P.O. Box 1567, Evanston, IL 60204.

Current Author Addresses: Dr. Tanus: Department of Medicine, Evanston Hospital, 2650 Ridge Avenue, Evanston, IL 60201.

Ms. Hantsch: Department of Medical Education, Northwestern University, McGaw Medical Center, 303 Chicago Avenue, Chicago, IL 60611.

Ann Intern Med. 1991;115(7):546-547. doi:10.7326/0003-4819-115-7-546
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This excerpt has been provided in the absence of an abstract.

Allergic bronchopulmonary aspergillosis, first described by Hinson and associates (1) in 1952, is a hypersensitivity reaction to the fungus Aspergillus. In patients with an underlying respiratory disorder such as asthma, the condition progresses to a fibrotic end stage unless it is detected early and treated aggressively with corticosteroids (2). The condition has been recognized more frequently in recent years, and the diagnosis is based on a combination of clinical, immunologic, and radiologic criteria (3). Characteristics of the condition include peripheral blood eosinophilia, immunologic reactivity to Aspergillus antigen, increased serum immunoglobulin E levels, central bronchiectasis, and pulmonary infiltrates. No cases of


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