0

The full content of Annals is available to subscribers

Subscribe/Learn More  >
Brief Reports |

Effects of Long-term Sulindac Therapy on Colonic Polyposis

Joaquim Rigau, MD; Josep M. Piqué, MD; Elisa Rubio, MD; Ramón Planas, MD; Josep M. Tarrech, MD; and Josep M. Bordas, MD
[+] Article and Author Information

Grant Support: In part by Fundació Catalana per les Malaties del Fetge i Gastroenterològiques.

Requests for Reprints: Josep M. Piqué, MD, Gastroenterology Department, Hospital Clínic, Barcelona University, Villarroel 170, 08036 Barcelona, Spain.

Current Author Addresses: Drs. Rigau, Rubio, and Tarrech: Hospital General de Granollers, Departments of Medecine and Surgery, Granollers, Barcelona, Spain.

Drs. Piqué and Bordas: Hospital Clínic, Barcelona University, Gastroenterology Department, Villarroel 170, 08036 Barcelona, Spain.

Dr. Planas: Hospital Germans Trias i Pujol, Gastroenterology Department, Crta. Cañet, Badalona, Barcelona, Spain.


Ann Intern Med. 1991;115(12):952-954. doi:10.7326/0003-4819-115-12-952
Text Size: A A A
This excerpt has been provided in the absence of an abstract.

Sulindac treatment has been reported to induce marked reductions in the number and size of adenomatous polyps in the rectal segment after subtotal colectomy (1). These findings were not conclusive, however, because spontaneous remission of rectal adenomas after colectomy and ileorectal anastomosis has been described in patients with familial polyposis (2). Gonzaga and co-workers (3) and Wadell and associates (4) have described patients for whom sulindac treatment has led to a decrease in diffuse adenomatous polyps in intact colons. We report our experience with seven patients having diffuse colonic polyposis treated with sulindac. Endogenous prostaglandin generation in the colonic mucosa

...

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Letters

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Comments

Submit a Comment
Submit a Comment

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.

Toolkit

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Advertisement
Related Articles
Journal Club
Related Point of Care
Topic Collections
PubMed Articles

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.
(Required)
(Required)