0

The full content of Annals is available to subscribers

Subscribe/Learn More  >
Brief Reports |

Low-Dose Splenic Irradiation in the Treatment of Autoimmune Thrombocytopenia in HIV-infected Patients

Samuel W. Needleman, MD; James Sorace, MD; and Hipolito Poussin-Rosillo, MD
[+] Article and Author Information

Grant Support: Dr. Needleman is the recipient of VA Research Career Development Award RA 1596.

Requests for Reprints: Samuel W. Needleman, MD, Medicine Service (111), Baltimore Department of Veterans Affairs Medical Center, 3900 Loch Raven Boulevard, Baltimore, MD 21218.

Current Author Addresses: Drs. Needleman and Sorace: Baltimore Department of Veterans Affairs Medical Center, 3900 Loch Raven Boulevard, Baltimore, MD 21218.

Dr. Poussin-Rosillo: Department of Radiation Oncology, University of Maryland Hospital, 22 S. Greene Street, Baltimore, MD 21201.


Ann Intern Med. 1992;116(4):310-311. doi:10.7326/0003-4819-116-4-310
Text Size: A A A
This excerpt has been provided in the absence of an abstract.

Autoimmune thrombocytopenic purpura (AITP) is one of many compli-cations associated with human immunodeficiency virus (HIV) type-1 infections (1, 2). Circulating immune complexes (3), antiplatelet antibodies (4, 5), and anti-idiotype antibody formation (6) have each been suggested to play a role in its pathogenesis.

Treatment of AITP in HIV-infected patients is difficult for two reasons. Established therapies for AITP (that is, corticosteroids) may be associated with an increased risk in patients with HIV infection because they superimpose an additional immunosuppressive burden and thus might increase the rate of opportunistic infection (7). Splenectomy, although offering remission rates in HIV-infected patients comparable to

...

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Letters

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Comments

Submit a Comment
Submit a Comment

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.

Toolkit

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Advertisement
Related Articles
Topic Collections
PubMed Articles
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.
(Required)
(Required)