0

The full content of Annals is available to subscribers

Subscribe/Learn More  >
Brief Reports |

Conjugal Graves Disease

Susana A. Ebner, MD; Marie-Claude Badonnel, PhD; Lawrence K. Altman, MD; and Lewis E. Braverman, MD
[+] Article and Author Information

Grant Support: In part by Grant DK18919; National Institutes of Diabetes, Digestive and Kidney Diseases; National Institutes of Health, Bethesda, Maryland.

Requests for Reprints: Lewis E. Braverman, MD, University of Massachusetts Medical Center, Division of Endocrinology, 55 Lake Avenue North, Worcester, MA 01655.

Current Author Addresses: Drs. Ebner, Badonnel, and Braverman: University of Massachusetts Medical Center, Division of Endocrinology, 55 Lake Avenue North, Worcester, MA 01655.

Dr. Altman: New York Times, 229 West 43 Street, New York, NY 10036.


Ann Intern Med. 1992;116(6):479-481. doi:10.7326/0003-4819-116-6-479
Text Size: A A A
This excerpt has been provided in the absence of an abstract.

Hyperthyroid Graves disease is an autoimmune disorder characterized by thyrotoxicosis, diffuse goiter, and antibodies directed against the thyrotropin (TSH) receptor, thyroglobulin (Tg), and thyroid peroxidase (TPO). The TSH receptor antibody is believed to stimulate the generation of cAMP in the thyroid, resulting in the increased synthesis and release of the thyroid hormones. The abnormal function of the immune system found in patients with this disease is strongly linked to a genetic predisposition. The incidence of thyroid disease among monozygotic twins is approximately 50%. This lack of complete concordance suggests that environmental factors, including infectious agents such as Yersinia enterocolitica (1)

...

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Letters

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Comments

Submit a Comment
Submit a Comment

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.

Toolkit

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Advertisement
Related Articles
Topic Collections
PubMed Articles

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.
(Required)
(Required)