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The Air Crescent Sign Caused by Staphylococcus aureus Lung Infection in a Neutropenic Patient with Leukemia

Wayne Gold, MD; Hillar Vellend, MD; and James Brunton, MD
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Requests for Reprints: James Brunton, MD, Department of Microbiology and Infectious Diseases, The Toronto Hospital (General Division), 200 Elizabeth Street, NUW 13-124, Toronto, Ontario, Canada M5G 2C4.

Current Author Addresses: Drs. Gold and Brunton: Department of Microbiology and Infectious Diseases, The Toronto Hospital (General Division), 200 Elizabeth Street, NUW 13-124, Toronto, Ontario, Canada M5G 2C4.

Dr. Vellend: Mount Sinai Hospital, Suite 415, 600 University Avenue, Toronto, Ontario, Canada M5G 1X5.

Ann Intern Med. 1992;116(11):910-911. doi:10.7326/0003-4819-116-11-910
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This excerpt has been provided in the absence of an abstract.

The radiographic air crescent sign is seen in several clinical conditions (1, 2). Angioinvasive aspergillosis is the most common cause of this sign in the immunocompromised host (3, 4). We report the case of a patient with acute lymphoblastic leukemia who developed the air crescent sign as a result of Staphylococcus aureus lung infection.

Case Report: A previously healthy 18-year-old man presented in August 1991 with a 3-month history of fatigue; in addition, during the 3 weeks before presentation, he experienced headache, bruising, and a 4.5-kg weight loss. Physical examination revealed widespread ecchymoses of the upper and lower extremities, generalized


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