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Complications of Chronic Liver Disease

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Rector WG.  ed. 383 pages. St. Louis: : Mosby Year Book, Inc; ; 1992.. $65.00.

Ann Intern Med. 1992;117(6):543-544. doi:10.7326/0003-4819-117-6-543_4
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Remarkable advances in the diagnosis and treatment of patients with liver disease have occurred in the last decade. The identification of the hepatitis C virus, the introduction of alpha-interferon into clinical practice, and promising results with ursodeoxycholic acid for cholestatic liver disease are examples that come to mind. Undoubtedly, the most important factor in the changing practice of hepatology is the emergence of liver transplantation as definitive therapy for end-stage liver disease. These advances have changed hepatology from a descriptive speciality into an increasingly therapeutic one. The availability of liver transplantation, in particular, emphasizes the need to optimize treatment of


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